Post-Ictal Heart Rate Oscillations in Partial Epilepsy: Data and Analysis

The new PhysioNet website is available at: https://physionet.org. We welcome your feedback.

This database is described in

Al-Aweel IC, Krishnamurthy KB, Hausdorff JM, Mietus JE, Ives JR, Blum AS, Schomer DL, Goldberger AL. Post-Ictal Heart Rate Oscillations in Partial Epilepsy. Neurology 53(7):1590-1592 (1999 October 22).

Please cite this publication when referencing this material, and also include the standard citation for PhysioNet:

Goldberger AL, Amaral LAN, Glass L, Hausdorff JM, Ivanov PCh, Mark RG, Mietus JE, Moody GB, Peng C-K, Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals. Circulation 101(23):e215-e220 [Circulation Electronic Pages; http://circ.ahajournals.org/content/101/23/e215.full]; 2000 (June 13).
sample waveform

The authors of the first reference above report “post-ictal heart rate oscillations in a heterogeneous group of patients with partial epilepsy. This pattern is marked by the appearance of transient but prominent low-frequency heart rate oscillations (0.01 - 0.1 Hz) immediately following five of 11 seizures recorded in five patients. This finding may be a marker of neuroautonomic instability, and, therefore, may have implications for understanding perturbations of heart rate control associated with partial seizures.”

The annotated ECG recordings on which this study was based may be downloaded from this page. Each recording consists of a (text) header file (with suffix .hea), a (binary) signal file (with suffix .dat), and a (binary) annotation file (with suffix .ari); these files may be read using the WFDB software package. The text file times.seize indicates the intervals of the seizure in each recording, based on simultaneously recorded EEGs (not available).

Icon  Name                    Last modified      Size  Description
[DIR] Parent Directory                             -   
[   ] ANNOTATORS              14-Oct-2000 04:36   58   list of annotators
[   ] DOI                     21-Sep-2015 19:00   19   
[   ] MD5SUMS                 13-Jul-2005 08:26  1.4K  
[   ] RECORDS                 29-Mar-2000 17:13   35   list of record names
[   ] SHA1SUMS                13-Jul-2005 08:26  1.7K  
[   ] SHA256SUMS              18-Sep-2007 18:40  2.6K  
[TXT] local.css               28-Oct-2015 23:32  3.1K  
[   ] sz01.ari                01-May-1998 18:49   16K  unaudited annotations
[   ] sz01.dat                01-May-1998 18:49  2.1M  digitized signal(s)
[   ] sz01.hea                06-Apr-2008 00:05   57   header file
[   ] sz01.hea-               04-Nov-1999 21:29   62   header file
[XWS] sz01.xws                12-Dec-1999 23:33   89   WAVEScript
[   ] sz02.ari                27-Mar-1998 18:45   26K  unaudited annotations
[   ] sz02.dat                26-Mar-1998 18:35  4.8M  digitized signal(s)
[   ] sz02.hea                06-Apr-2008 00:05   57   header file
[   ] sz02.hea-               04-Nov-1999 21:29   62   header file
[XWS] sz02.xws                12-Dec-1999 23:33   89   WAVEScript
[   ] sz03.ari                27-Mar-1998 18:40   32K  unaudited annotations
[   ] sz03.dat                26-Mar-1998 18:37  5.2M  digitized signal(s)
[   ] sz03.hea                06-Apr-2008 00:05   56   header file
[   ] sz03.hea-               04-Nov-1999 21:29   61   header file
[XWS] sz03.xws                12-Dec-1999 23:33   89   WAVEScript
[   ] sz04.ari                27-Mar-1998 18:50   12K  unaudited annotations
[   ] sz04.dat                26-Mar-1998 18:40  2.1M  digitized signal(s)
[   ] sz04.hea                06-Apr-2008 00:05   56   header file
[   ] sz04.hea-               04-Nov-1999 21:29   61   header file
[XWS] sz04.xws                12-Dec-1999 23:33   89   WAVEScript
[   ] sz05.ari                16-Jul-1998 17:29   16K  unaudited annotations
[   ] sz05.dat                26-Mar-1998 21:00  2.1M  digitized signal(s)
[   ] sz05.hea                06-Apr-2008 00:05   56   header file
[   ] sz05.hea-               04-Nov-1999 21:29   61   header file
[XWS] sz05.xws                12-Dec-1999 23:33   89   WAVEScript
[   ] sz06.ari                30-Jul-1998 18:52   25K  unaudited annotations
[   ] sz06.dat                26-Mar-1998 21:02  4.1M  digitized signal(s)
[   ] sz06.hea                06-Apr-2008 00:05   56   header file
[   ] sz06.hea-               04-Nov-1999 21:29   61   header file
[XWS] sz06.xws                12-Dec-1999 23:33   89   WAVEScript
[   ] sz07.ari                22-May-1998 20:52   35K  unaudited annotations
[   ] sz07.dat                01-May-1998 18:50  2.7M  digitized signal(s)
[   ] sz07.hea                06-Apr-2008 00:05   56   header file
[   ] sz07.hea-               04-Nov-1999 21:29   61   header file
[XWS] sz07.xws                12-Dec-1999 23:33   89   WAVEScript
[TXT] szdb.shtml              06-Jan-2012 03:02   11K  
[   ] times.seize             04-Nov-1999 21:29  230

Questions and Comments

If you would like help understanding, using, or downloading content, please see our Frequently Asked Questions.

If you have any comments, feedback, or particular questions regarding this page, please send them to the webmaster.

Comments and issues can also be raised on PhysioNet's GitHub page.

Updated Friday, 28-Oct-2016 22:58:42 CEST
PhysioNet is supported by the National Institute of General Medical Sciences (NIGMS) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under NIH grant number 2R01GM104987-09.